Generative House is a collaborative exploration of advanced technologies for lower- and working-class housing carried out by industrial and academic partners in southern Brazil. It seeks to test generative procedures and digital manufacturing to develop a flexible building system for low-cost sustainable housing in order to inspire future developments in this field by developing an urban grammar through manufacturing models and generative programming, as well as the parametric design of panels assembled using digital fabrication. Scale models and full-scale prototypes with timber boards have been built, demonstrating the feasibility of the approach proposed. However, further refinement of the adopted procedures and technical applications is required.